Non-diabetic | Diabetic | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|

%β | %S | Proinsulin | %β | %S | Proinsulin | ||||||||||||||

r_{s} | p Value | r_{s} | p Value | r_{s} | p Value | r_{s} | p Value | r_{s} | p Value | r_{s} | p Value | ||||||||

Spectral measures of heart rate variability
| |||||||||||||||||||

LF | 0.31 | 0.14 | −0.15 | 0.48 | −0.29 | 0.25 | 0.10 | 0.64 | 0.27 | 0.20 | −0.23 | 0.29 | |||||||

HF | 0.46 | 0.02 | −0.29 | 0.18 | −0.29 | 0.26 | −0.10 | 0.64 | 0.14 | 0.53 | −0.25 | 0.26 | |||||||

Non-spectral measures of heart rate variability
| |||||||||||||||||||

SDANN | 0.20 | 0.35 | −0.12 | 0.56 | −0.45 | 0.06 | −0.29 | 0.18 | 0.45 | 0.03 | −0.14 | 0.51 | |||||||

SD | 0.19 | 0.37 | −0.08 | 0.70 | −0.38 | 0.12 | −0.08 | 0.71 | 0.33 | 0.12 | −0.21 | 0.34 | |||||||

rMSSD | 0.31 | 0.14 | −0.23 | 0.29 | −0.27 | 0.28 | −0.20 | 0.35 | 0.17 | 0.43 | −0.12 | 0.58 | |||||||

pMN50 | 0.39 | 0.06 | −0.24 | 0.25 | −0.29 | 0.25 | −0.15 | 0.48 | 0.14 | 0.52 | −0.09 | 0.69 | |||||||

SDNN | 0.17 | 0.42 | −0.08 | 0.70 | −0.46 | 0.06 | −0.24 | 0.26 | 0.48 | 0.02 | −0.21 | 0.36 | |||||||

Clinical tests | |||||||||||||||||||

Valsalva ratio | 0.03 | 0.90 | −0.11 | 0.62 | 0.24 | 0.33 | −0.45 | 0.03 | 0.10 | 0.63 | −0.07 | 0.74 | |||||||

Respiratory variation (beats/min) | −0.24 | 0.26 | −0.09 | 0.67 | 0.14 | 0.58 | −0.06 | 0.77 | −0.07 | 0.75 | −0.10 | 0.67 | |||||||

30:15 heart rate ratio | −0.24 | 0.25 | −0.02 | 0.93 | 0.14 | 0.59 | −0.18 | 0.39 | 0.46 | 0.02 | −0.21 | 0.34 | |||||||

Supine/standing fall in systolic pressure (mm Hg) | −0.13 | 0.55 | −0.07 | 0.76 | −0.20 | 0.44 | −0.18 | 0.40 | 0.19 | 0.38 | −0.23 | 0.32 | |||||||

Increase in diastolic pressure; handgrip (mm Hg) | −0.05 | 0.83 | 0.27 | 0.19 | −0.28 | 0.25 | −0.21 | 0.33 | 0.13 | 0.53 | 0.02 | 0.93 |

HF, high frequency; LF, low frequency; pNN50, proportion of adjacent RR intervals more than 50 ms different; rMSSD, root mean square of difference of successive RR intervals;

*r*_{s}, Spearman correlation coefficient; SD, mean of all five minute standard deviations of RR intervals; SDANN, standard deviation of five minute RR intervals; SDNN, standard deviation of all RR intervals from the mean.